Protein Domain : DOMON domain-containing protein FRRS1L IPR042789

Type  Family
Description  Ferric Chelate Reductase 1 Like protein (FRRS1L) interacts with both GluA1 and GluA2 subunits of AMPA receptors (AMPARs). It plays an important role in the regulation of excitatory synaptic strength [ ]. Mutations in the FRRS1L gene cause epileptic encephalopathy, early infantile, 37 (EIEE37), a form of epileptic encephalopathy, a heterogeneous group of severe childhood onset epilepsies characterised by refractory seizures, neurodevelopmental impairment, and poor prognosis [, ].
Short Name  FRRS1L

0 Child Features

0 Gene Families

0 Genes

1 Ontology Annotations

0 Parent Features

0 Publications

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