v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | This family includes Beta-catenin-interacting protein 1 (CTNNBIP1, also known as ICAT) and protein LZIC from chordates. CTNNBIP1 is a suppressor of the Wnt/beta-catenin signaling pathway. It negatively regulates beta-catenin co-transcriptional activity by competing with TCF/LEF factors in their binding to beta-catenin superhelical core [ , , ].Protein LZIC contains a leucine zipper domain and an ICAT homologous domain, with particular conservation of residues that are used by ICAT for beta-catenin-binding [ , ]. |
| Short Name | CTNNBIP1/LZIC |