Protein Domain : Coiled-coil domain-containing protein 74A/74B/92 IPR040370

Type  Family
Description  This entry includes coiled-coil domain-containing proteins 74A (CCDC74A), 74B (CCDC74B) and 92 (CCDC92).Coiled-coil domain-containing protein 92 (CCDC92) is an interferon-stimulated protein that plays a role in innate immunity. It strongly inhibits ebolavirus transcription and replication through the formation of a complex with viral RNA-bound nucleocapsid (NP) that prevents the transport of NP to the cell surface [ ]. It has also been shown to interact with centrosomal protein CEP164 [], which is required for primary (nonmotile) cilium formation [].
Short Name  CCDC74A/CCDC74B/CCDC92

0 Child Features

0 Gene Families

0 Genes

0 Ontology Annotations

0 Parent Features

0 Publications

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