Protein Domain : Homeobox-containing protein 1 IPR040363

Type  Family
Description  HMBOX1 binds to 5'-TTAGGG-3' repeats in telomeric DNA and may play a role in recruitment of the telomerase complex to telomeres [ , ]. It also plays a role in the alternative lengthening of telomeres (ALT) pathway in telomerase-negative cells where it promotes formation and/or maintenance of ALT-associated promyelocytic leukemia bodies (APBs) [].
Short Name  HMBOX1

0 Child Features

0 Gene Families

0 Genes

1 Ontology Annotations

0 Parent Features

0 Publications

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