Protein Domain : Autophagy-related protein 29 superfamily IPR039362

Type  Homologous_superfamily
Description  Autophagy-related (Atg) proteins play a role in autophagy. Atg29 forms a complex with Atg17 and Atg31. When autophagy is initiated, the Atg17-Atg31-Atg29 complex is first targeted to the phagophore assembly site (PAS) and then recruits other Atg proteins [ ]. The complex is recruited to the PAS by Atg11. Atg29 contains an N-terminal functional domain, whereas the C terminus plays a regulatory role. Phosphorylation of the C-terminal domain of Atg29 is required for its interaction with Atg11 and proper PAS localization [].The tertiary structure of Atg29 (within the Atg17-Atg29-Atg31 subcomplex) has been determined in part, showing a central three-helix bundle [ ].
Short Name  ATG29_sf

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