Protein Domain : CLAVATA3/ESR (CLE)-related protein 1-4 IPR039616

Type	Family
Description	This entry includes CLAVATA3/ESR (CLE)-related proteins 1-4 (CLE1/3/4) from Arabidopsis and CLE33 from Medicago truncatula. CLE33 is a signaling peptide involved in the regulation of root colonization by arbuscular mycorrhizal (AM) fungi. It moves from root to shoot to function with the receptor kinase SUNN, in a signaling pathway that repress strigolactone biosynthetic genes and strigolactone content in the roots, and consequently reduces the promotion of further colonization by AM fungi [ ].The CLE proteins share a C-terminal CLE domain with CLV3, a small secreted polypeptide that is active as a ligand and has a function in shoot apical meristem maintenance [ ]. In general, the CLE-related proteins are C-terminally processed to generate an active CLE peptide []. These small secreted peptide hormones then function in a variety of developmental and physiological processes [, ]. CLV3 and other A-type CLE peptides are involved in the suppression of stem cell development in root and shoot development, in contrast to the B-type CLE peptides, CLE41 and CLE44, in the case of Arabidopsis, which are not [].
Short Name	CLE1-4