Protein Domain : CLAVATA3/ESR (CLE)-related protein IPR039617

Type	Family
Description	This entry includes CLAVATA3/ESR (CLE)-related proteins 5, 6, 7, 12, 13 and 53. CLE12 and CLE13 control the nodule numbers by interacting with the SUPER NUMERIC NODULES (SUNN)-dependent auto-regulation of nodulation [ , ].This entry also includes CLE-4A-1 and CLE-4A-3 from Globodera rostochiensis (Golden nematode worm). They mimics host plant CLE extracellular signal peptides that regulate cell fate [ ].The CLE proteins share a C-terminal CLE domain with CLV3, a small secreted polypeptide that is active as a ligand and has a function in shoot apical meristem maintenance [ ]. In general, the CLE-related proteins are C-terminally processed to generate an active CLE peptide []. These small secreted peptide hormones then function in a variety of developmental and physiological processes [, ]. CLV3 and other A-type CLE peptides are involved in the suppression of stem cell development in root and shoot development, in contrast to the B-type CLE peptides, CLE41 and CLE44, in the case of Arabidopsis, which are not [].
Short Name	CLAVATA3-CLE