Protein Domain : AIP/AIPL1/TTC9 IPR039663

Type	Family
Description	Proteins in this entry have an N-terminal FKBP-type peptidyl-prolyl cis-trans isomerase domain followed by a C-terminal tetratricopeptide repeat-containing domain. Included in this entry are: aryl-hydrocarbon-interacting protein-like 1 (AIPL1), which is associated with inherited blindness and interacts with cell cycle regulator protein NUB1 [ ]; and AH receptor-interacting protein (AIP), which interacts with the tyrosine kinase receptor RET [], and mutations in AIP are associated with familial isolated pituitary adenomas [].This entry also matches Tetratricopeptide repeat protein 9 (TTC9). TTC9 contains tetratricopeptide repeat (TPR) domains constituted of the 34 amino acid consensus motif present in various number of tandem repeats [ ]. Tetratricopeptide repeat protein 9A (TTC9A) is involved anxiety-like behaviors through estrogen action in female mice [, ], and is thought to play a role in cancer cell invasion and metastasis [].
Short Name	AIP/AIPL1/TTC9