Protein Domain : Cartilage intermediate layer protein 1/2 IPR039675

Type  Family
Description  This entry includes cartilage intermediate layer proteins 1 (CILP1) and 2 (CILP2). CILP1 acts as a modulator of lumbar disc disease susceptibility [ ]. CILP1 interferes with pro-fibrotic TGFbeta signalling and is a mediator of cardiac extracellular matrix remodeling []. CILP2 is present in human articular cartilage and may be associated with collagen VI containing suprastructures [].
Short Name  CILP1/CILP2
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