Protein Domain : Developmental pluripotency-associated protein 2/4 IPR039590

Type  Family
Description  Developmental pluripotency-associated protein 2 (Dppa2, also known as ECAT15-2) and Dppa4 (also known as ECAT15-1) have a common DNA binding domain known as the SAP motif. Dppa2 has been found to bind to the regulatory region of Nkx2-5 in embryonic stem (ES) cells [ ]. Dppa4 has been found to bind to both DNA and histone H3 necessary for the chromatin structure resistance to MNase and for the proper localization of Dppa4 in ES cell nuclei [].
Short Name  Dppa2/4
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