Protein Domain : CUE domain-containing protein 2, CUE domain IPR039805

Type  Domain
Description  CUEDC2 is a novel negative regulator of progesterone receptor (PR) and functions to promote the progesterone-induced PR degradation by the ubiquitin-proteasome pathway [ ]. It also acts as the regulator of JAK1/STAT3 signaling through inhibiting cytokine-induced phosphorylation of JAK1 and STAT3 and the subsequent STAT3 transcriptional activity []. This entry represents the CUE domain found in CUEDC2.
Short Name  CUE_CUED2

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0 Gene Families

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0 Ontology Annotations

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