Protein Domain : Calcineurin B protein IPR015757

Type  Family
Description  Calcineurin is a Ser/Thr-specific calcium and calmodulin-dependent protein phosphatase that plays an essential role in the T cell activation pathway. Calcineurin and Nuclear factor of Activated T-cell (NFAT) proteins have been shown to participate in signalling cascades that govern the development and function of the immune, nervous, cardiovascular and musculoskeletal systems [ ]. Calcineurin is a heterodimeric protein consisting of: i) a catalytic subunit calcineurin A, which contains an active site dinuclear metal centre, and ii) a tightly associated, myristoylated, Ca(2+)-binding subunit, calcineurin B [].
Short Name  Calcineur_B

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2 Ontology Annotations

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