Protein Domain : Programmed cell death protein 4 IPR039778

Type  Family
Description  Programmed cell death protein 4 (PDCD4) binds to eukaryotic initiation factor 4A (eIF4A), inhibits translation initiation, and acts as a tumour suppressor. It contains two C-terminal MA3 domains that bind specifically to the eIF4A N-terminal domain (eIF4A-NTD) [ , , ].This entry also includes MRF1/2/3/4 from plants. They are involved in target of rapamycin (TOR)-egulated translation control, especially under energy-deficient conditions [ ].
Short Name  PDCD4

0 Child Features

0 Gene Families

0 Genes

1 Ontology Annotations

0 Parent Features

0 Publications

USDA
InterMine logo
The Legume Information System (LIS) is a research project of the USDA-ARS:Corn Insects and Crop Genetics Research in Ames, IA.
LegumeMine || ArachisMine | CicerMine | GlycineMine | LensMine | LupinusMine | PhaseolusMine | VignaMine | MedicagoMine
InterMine © 2002 - 2022 Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom