Protein Domain : Sequestosome-1, UBA domain IPR033741

Type  Domain
Description  This UBA domain is found in sequestosome-1 (SQSTM) and similar proteins [ ].Sequestosome-1 (SQSTM), also known as ubiquitin-binding protein p62, is a widely expressed multifunctional cytoplasmic protein that is able to noncovalently bind ubiquitin and several signaling proteins, suggesting a regulatory role connected to the ubiquitin-proteasome pathway. It functions as a scaffolding protein that regulates a diverse range of signaling pathways [ ]. It plays a critical role in cell's selective autophagy and oxidative stress response.
Short Name  SQSTM_UBA

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