Protein Domain : Nuclear transition protein 1 IPR001319

Type	Family
Description	Nuclear transition protein 1 (TP1) is one of the spermatid-specific proteins []. TP1 is a basic protein well conserved in mammalian species. In mammals, the second stage of spermatogenesis is characterised by the conversion of nucleosomal chromatin to the compact, non-nucleosomal and transcriptionally inactive form found in the sperm nucleus. This condensation is associated with a double-protein transition. The first transition corresponds to the replacement of histones by several spermatid-specific proteins (also called transition proteins) which are themselves replaced by protamines during the second transition.
Short Name	Nuclear_transition_prot1