Protein Domain : Outer membrane protein assembly factor BamA IPR023707

Type	Family
Description	This entry represents the BamA (also known as YaeT) family of proteins. BamA forms part of the outer membrane protein assembly complex, which is involved in assembly and insertion of β-barrel proteins into the outer membrane in Gram-negative bacteria [ ]. Contact-dependent growth inhibition (CDI) systems are widespread among Gram-negative bacteria, enabling them to bind to neighbouring bacterial cells and deliver protein toxins that inhibit cell growth. Escherichia coli EC93 CdiAEC93 recognised BamA protein as a receptor. The variations in the CdiAEC93-binding epitope (loops 6 and 7) of BamA restricts CDIEC93 target cell selection, and hence play a role in self-nonself discrimination [ ].
Short Name	OM_assembly_BamA