Protein Domain : Methyl-CpG-binding domain protein 5/6 IPR037385

Type  Family
Description  MBD5 and MBD6 are two members of the methyl-CpG-binding domain (MBD) family. They do not bind methylated DNA [ ], but instead they interact with the PR-DUB Polycomb protein complex in a mutually exclusive manner. They may share a function through their interaction with PR-DUB. MBD6, but not MBD5, is recruited to sites of DNA damage []. MBD5 is highly expressed in oocytes [].
Short Name  MBD5/MBD6

0 Child Features

0 Gene Families

0 Genes

0 Ontology Annotations

0 Parent Features

0 Publications

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