Protein Domain : Sfmbt, SAM domain IPR037605

Type  Domain
Description  Drosophila Sfmbt (dSfmbt) is part of the Pho repressive complex (PhoRC) responsible for HOX (Homeobox) gene silencing. In this complex, Pho or Pho-like proteins bind DNA and dSfmbt binds methylated histones. dSfmbt contains a SAM (sterile alpha motif) domain and 4 MBT repeats. dSfmbt can interact with mono- and di-methylated histones H3 and H4 through the MBT repeats [ ]. It also interacts with the PcG protein Scm, a related MBT-repeat protein with similar methyl-lysine binding activity [].This entry represents the SAM domain, which is a putative protein-protein interaction domain.
Short Name  Sfmbt_SAM

0 Child Features

0 Gene Families

0 Genes

1 Ontology Annotations

1 Parent Features

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