Protein Domain : Transthyretin-like IPR001534

Type	Family
Description	Transthyretin-related proteins form a nematode-specific expanded protein family that comprises 59 members, 54 of which are predicted to be secreted. The proteins show weak similarity to transthyretin (formerly called prealbumin) which transports thyroid hormones. [ ]. Some transthyretin-related genes are induced in response to environmental challenges such as oxidative stress or pathogen exposure. These proteins possess 4 cysteine residues that are conserved within the C. elegans transthyretin-related protein family, which could serve as reactive oxygen sensors or scavengers [].Transthyretin-related protein 52 (TTR-52), a member of this family, is required for efficient cell corpse engulfment by the recognition the surface exposed phosphatidylserine (PS). TTR-52 mediates recognition of apoptotic cells by cross-linking the PS signal with the phagocyte receptor CED-1 [ ].
Short Name	Transthyretin-like