Protein Domain : Methyl-CpG binding protein 2/3, C-terminal domain IPR025884

Type  Domain
Description  CpG-methylation is a frequently occurring epigenetic modification of vertebrate genomes resulting in transcriptional repression. This domain is found at the C terminus of the methyl-CpG-binding domain (MBD) containing proteins MBD2 [ ] and MBD3 []. The latter was shown to not bind directly to methyl-CpG DNA but rather interact with components of the NuRD/Mi2 complex [], an abundant deacetylase complex.
Short Name  MeCpG-bd_2/3_C_dom

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