Protein Domain : FPRL1 inhibitory protein IPR023256

Type  Family
Description  Formyl Peptide Receptor-Like 1 (FPRL1)-inhibitory protein (also termed FLIPr) has been shown to inhibit calcium mobilisation in neutrophils [ ]. There is evidence that FLIPr binds to FPRL1 and, at higher concentrations, to FPR [], impairing the leukocyte response to FPRL1 agonists. It has revealed unknown inflammatory ligands during S.aureus infection and, as an FPRL1 antagonist, may facilitate development of therapeutic agents in FPRL1-mediated inflammatory diseases [].
Short Name  FLIPR

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0 Ontology Annotations

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