Protein Domain : DENN domain-containing protein 5A/B IPR047278

Type  Family
Description  This entry includes DENN domain-containing proteins 5A/B (DEN5A/B) from humans and similar animal proteins that belong to the RAB6 interacting protein 1 (Rab6IP1) family. DEN5A/B are guanine nucleotide exchange factors (GEFs) which may activate RAB6A and RAB39A and/or RAB39B. They promote the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form [ ]. DEN5A is involved in the negative regulation of neurite outgrowth [].
Short Name  DEN5A/B

0 Child Features

0 Gene Families

0 Genes

0 Ontology Annotations

0 Parent Features

0 Publications

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