Protein Domain : Aflatoxin regulatory protein IPR013700

Type	Domain
Description	Aflatoxins belong to a family of decaketides that are produced as secondary metabolites by Aspergillus flavus and Aspergillus parasiticus [ ]. The aflatoxin biosynthetic pathway involves several enzymatic steps that appear to be regulated by the aflR genes in A. flavus and A. parasiticus. AflR encodes a protein that contains a cysteine-rich motif. Several fungal transcriptional activator proteins contain this motif, which binds DNA in a zinc-dependent fashion (occurs in fungal transcriptional regulatory proteins) [, ].This domain is found in the aflatoxin regulatory protein (AflR) and related fungal sequences. AflR is involved in the regulation of the biosynthesis of aflatoxin in the fungal genus Aspergillus [ ]. It occurs together with the fungal Zn(2)-Cys(6) binuclear cluster domain (). This entry also includes Sterigmatocystin biosynthesis regulatory protein [ ]. Sterigmatocystin is related to aflatoxin.
Short Name	AflR