v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | This entry represents a protein family that includes the transcription factors Forkhead box protein N2-4 from humans (FOXN2-4) and related proteins from animals [ , ]. Putative forkhead-related transcription factor fkh-5 from Caenorhabditis elegans, an orthologue of human FOXN4, is also included in this entry. FOXN4 is a transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. It binds to a consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling [, ]. |
| Short Name | FOXN2-4-like |