Protein Domain : F-box only protein 7 IPR047118

Type  Family
Description  This family includes F-box only protein 7 from humans (Fbxo7) and similar animal proteins. Fbxo7 is the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. It plays a role in the clearance of damaged mitochondria via selective autophagy (mitophagy). Mutations in this protein lead to Parkinson's disease [ , , , ].
Short Name  Fbxo7

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0 Gene Families

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0 Ontology Annotations

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