Protein Domain : Outer surface lipoprotein domain superfamily IPR023322

Type  Homologous_superfamily
Description  The ospA and ospB genes encode the major outer membrane proteins of the Lyme disease spirochaete Borrelia burgdorferi [ ]. The deduced gene products OspA and OspB, contain 273 and 296 residues respectively []. The two Osp proteins show a high degree of sequence similarity, indicating a recent evolutionary event. Molecular analysis and sequence comparison of OspA and OspB with other proteins has revealed similarity to the signal peptides of prokaryotic lipoproteins [, ].This superfamily represents a structural domain, which consists of 21 stranded sheet partly folded upon itself at the ends, found in outer surface lipoproteins.
Short Name  OM_lipoprot_dom_sf

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