Protein Domain : Death domain-containing protein CRADD IPR037939

Type  Family
Description  CRADD (Caspase and RIP adaptor, also known as RAIDD) is an adaptor protein that together with the p53-inducible protein PIDD and caspase-2, forms the PIDDosome complex, which is required for caspase-2 activation and plays a role in mediating stress-induced apoptosis [ ]. It contains an N-terminal CARD, which interacts with the caspase-2 CARD, and a C-terminal Death domain (DD), which interacts with the DD of PIDD [].
Short Name  CRADD

0 Child Features

0 Gene Families

0 Genes

2 Ontology Annotations

0 Parent Features

0 Publications

USDA
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