Protein Domain : Recombination protein RecR, C4-type zinc finger IPR023628

Type	Domain
Description	The bacterial protein RecR is an important regulator in the RecFOR homologous recombination pathway during DNA repair [ , , , ]. It acts with RecF and RecO forming a complex that facilitates the loading of RecA onto ssDNA [, ]. RecR is a zinc metalloprotein consisting of a N-terminal helix-hairpin-helix (HhH) motif, a middle region containing a zinc finger motif and a Toprim domain, and a C-terminal domain comprising a divergent Walker B motif and a C-terminal helix [, ]. This entry represents the C4-type zinc finger domain which contains four strictly conserved cysteine residues that coordinates a zinc ion [ , ]. This domain plays an important role, maintaining the stability of the 3D structure [].
Short Name	Rcmb_RecR_C4-type_Zn