Protein Domain : Fasciculation and elongation protein zeta, FEZ IPR011680

Type  Family
Description  The first member of the FEZ (fasciculation and elongation protein zeta) family identified was unc-76, from C. elegans. The protein is necessary for normal axon fasciculation and is required for axon-axon interactions [ ]. Later, two human homologues, FEZ1 and FEZ2, were identified [ ]. FEZ1 and FEZ2 interact with PKCzeta and have been shown to induce neurite extension of PC12 cells when co-expressed with a constitutively active mutant of PKCzeta [].
Short Name  FEZ

0 Child Features

0 Gene Families

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0 Ontology Annotations

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