v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | AKIP1 regulates the effect of the cAMP-dependent protein kinase (PKAc) signalling pathway on the NF-kB activation cascade [ , ]. AKIP1 binds PKA [] and co-localises with the NF-kB subunit p65 []. In humans, there are three splice variants, whereas only the full-length protein is present in rodents []. AKIP1 seems to act as a modulator of PKA in NF-kappaB signalling; different splice variants have been shown to repress [] or enhance NF-kB transcription []. |
| Short Name | AKIP1 |