Protein Domain : Early E3 14.5kDa protein IPR008131

Type  Family
Description  The E3B 14.5kDa was first identified in human adenovirus type 5. It is an integral membrane protein oriented with its C terminus in the cytoplasm. It functions to down-regulate the epidermal growth factor receptor and prevent tumour necrosis factor cytolysis. It achieves this through the interaction with E3 10.4kDa protein [ , ].
Short Name  Adeno_E3_14_5
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