Protein Domain : Protein Z-dependent peptidase inhibitor, serpin domain IPR033835

Type  Domain
Description  Protein Z-dependent protease inhibitor (ZPI; MEROPS identifier I04.005) is a member of the serpin superfamily of proteinase inhibitors, corresponding to clade A10 [ , ]. ZPI inhibits coagulation factor Xa, dependent on protein Z (PZ), a vitamin K-dependent plasma protein []. ZPI also inhibits factor XIa in a process that does not require PZ []. In general, SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms [].
Short Name  PZI_serpin_dom

0 Child Features

0 Gene Families

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2 Ontology Annotations

1 Parent Features

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