Protein Domain : F-box only protein FBXO9/FBXO48 IPR045118

Type	Family
Description	This entry represents a group of F-box only proteins, including FBXO9/48 from animals, Pof7/Hrt3 from yeasts and SKIP32 from plants. Hrt3 is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins [ ]. FBXO9 is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of TTI1 and TELO2 in a CK2-dependent manner, thereby directly regulating mTOR signalling []. GID2 (also known as SLEEPY 1) is an essential component of the SCF-type E3 ligase complex, SCF(GID2), a complex that positively regulates the gibberellin signalling pathway [].
Short Name	FBXO9/FBXO48