v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | This family includes vacuolar protein 8 (Vac8), an armadillo repeat-containing protein that functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole [ , ]. Its structure has a N-terminal flexible H1 helix followed by 12 armadillo repeats that form a right-handed superhelical structure []. The cationic triad (Arg276, Arg317, and Arg359) motifs in this protein are critical for the interaction with the nuclear membrane protein Nvj1 to form a nucleus-vacuole junction (NVJ) and for the recognition of Atg13, a key component of the cytoplasm-to-vacuole targeting (CVT) pathway []. |
| Short Name | Vac8 |