Protein Domain : Vacuolar protein 8 IPR045156

Type  Family
Description  This family includes vacuolar protein 8 (Vac8), an armadillo repeat-containing protein that functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole [ , ]. Its structure has a N-terminal flexible H1 helix followed by 12 armadillo repeats that form a right-handed superhelical structure []. The cationic triad (Arg276, Arg317, and Arg359) motifs in this protein are critical for the interaction with the nuclear membrane protein Nvj1 to form a nucleus-vacuole junction (NVJ) and for the recognition of Atg13, a key component of the cytoplasm-to-vacuole targeting (CVT) pathway [].
Short Name  Vac8

0 Child Features

0 Gene Families

0 Genes

2 Ontology Annotations

0 Parent Features

0 Publications

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