LIS - Legume Information System
Information about legume traits for crop improvement
CicerMine
v5.1.0.3
Cicer data from the Legume Information System
v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | This entry represents a group of AAA domain-containing protein, including ATAD2/ATD2B from humans, Tat-binding homolog 7 from Caenorhabditis elegans (Lex-1) and Saccharomyces cerevisiae (Yta7), and ATPase with bromodomain protein abo1/2 from S. pombe. ATPase family AAA domain-containing protein 2, also known as ANCCA, is a transcriptional coactivator for estrogen-bound estrogen receptor (ER) alpha and androgen receptor [ , ]. It is required for coregulator occupancy and chromatin modification []. ANCCA is also required for recruiting specific E2Fs to their targets and for the assembly of the HCF-MLL hKMT complex, a complex that regulates cell cycle progression []. Overexpression of ANCCA has been linked to various cancers [, , ].In Caenorhabditis elegans, Lex-1 affects chromatin structure and promotes expression from repetitive sequences [ ].In Saccharomyces cerevisiae, Yta7 binds to histones and regulates transcription of histones and other gene [ ]. |
| Short Name | ATAD2-like |
