Protein Domain : Agglutinin-like protein, N-terminal, N2 subdomain IPR043063

Type	Homologous_superfamily
Description	Candida albicans is the most prevalent fungal pathogen in humans and a major source of life-threatening nosocomial infections [ ]. It codes for several cell surface Als (agglutinin-like sequence) glycoproteins (Als1-Als7 and Als9) which are key virulence factors and have been associated with binding of host-cell surface proteins and small peptides of random sequence, the formation of biofilms and amyloid fibres. The N-terminal domain of Als proteins (NT-Als) is involved in adhesive function and comprises two tandem DEv-IgG type immunoglobulin domains, N1 and N2, arranged in a fold similar to that of the MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules) domain []. It also possesses a peptide-binding cavity (PBC) that can bind peptides with broad specificity.This superfamily represents the N2 subdomain found in the N-terminal of Als proteins.
Short Name	Agglutinin-like_N_N2