Protein Domain : Intraflagellar transport protein 25 IPR033558

Type  Family
Description  Intraflagellar transport (IFT) is the bidirectional movement of multimeric protein particles, termed IFT particles, between the cell body and the distal tip of a flagellum. IFT particle proteins are thought to serve as scaffolds to facilitate the attachment of cargo proteins to IFT motors, mediating the transport of flagellar precursors [ ]. The main constituents of IFT particles are organized into two protein complexes, A and B.IFT25 is a component of the intraflagellar transport (IFT) complex B. It directly interacts with IFT27, forming a subcomplex that may be involved in the regulation of IFT [ , ]. IFT25 is required for Hedgehog signalling in cilia [].
Short Name  IFT25

0 Child Features

0 Gene Families

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2 Ontology Annotations

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