Protein Domain : Intracellular lipid binding protein IPR031259

Type	Family
Description	Fatty acid binding proteins (FABPs) and cellular retinoic-acid-binding proteins (CRBPs) are part of the intracellular-lipid-binding proteins (iLBPs) family [].The primary role of all the FABP members is regulation of fatty acid uptake and intracellular transport [ ]. To date, nine FABPs have been identified in mammals, each showing specific tissue distribution patterns and ligand preference. All FABP members have a similar β-barrel structure; fatty acid ligands are accommodated in the central cavity of the β-barrel, which dramatically increases their solubility in the aqueous cytoplasm, facilitating their movement to target sites [, ].Retinoic-acid-binding proteins (CRBPs) are specific for vitamin A derivatives and can be classified into the cellular retinoic acid-binding proteins (CRABP-I and II) and the cellular retinol-binding proteins (CRBP-I, II, III, and IV) [ ].
Short Name	ILBP