Protein Domain : Plexin domain-containing protein IPR031152

Type  Family
Description  Plexin domain-containing protein 1 (TEM7) and plexin domain-containing protein 2 (TEM7R) were identified as tumour endothelial markers (TEMs) that displayed elevated expression during tumour angiogenesis [ ]. TEM7 encodes a type I transmembrane protein with a large extracellular domain, a hydrophobic transmembrane domain, and a short cytoplasmic tail. Its cell surface expression is essential during endothelial cell capillary morphogenesis [].
Short Name  PLXDC

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