LIS - Legume Information System
Information about legume traits for crop improvement
CicerMine
v5.1.0.3
Cicer data from the Legume Information System
v5.1.0.3
Cicer data from the Legume Information System
| Description | This is a family of unknown function. Family members are found in Bacteria and Eukaryotes. In algae, this family is found on the N-terminal of diphthamide synthase family Pfam:PF01902 and is predicted to be a membrane transporter belonging to The ATP-binding Cassette (ABC) family [1]. In nematoda, it is found on the N-terminal side of ribosomal protein family L14 Pfam:PF00238. It is also found on the N-terminal of Cob(I)alamin adenosyltransferase Pfam:PF01923 in other eukaryotes. Family members found in homo sapiens such as Swiss:Q5VUE5, have been shown to be highly expressed in 15 high-grade neuroendocrine tumor cell lines and YAP1-positive small-cell lung cancer cell lines [2] as well as being up-regulated in two human Multiple Myloma cell lines in response to selective nuclear export inhibitor KPT-276 [3]. The HMM profile of this family reveals 4 highly conserved cysteines. |
| Namespace | Family |
