GO Term : GO:0043765 T/G mismatch-specific endonuclease activity Gene Ontology

Description  Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine.
Namespace  molecular_function
Obsolete  false

0 Cross References

0 Data Sets

1 Ontology

Trail: GOTerm

0 Ontology Annotations

10 Parents

Trail: GOTerm

9 Relations

Trail: GOTerm

4 Synonyms

Trail: GOTerm
USDA
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