Protein Domain : Integral membrane protein TerC, riboswitch-linked IPR022369

Type	Family
Description	A family containing a number of integral membrane proteins is named after TerC protein. TerC has been implicated in resistance to tellurium, and may be involved in efflux of tellurium ions. The tellurite-resistant Escherichia coli strain KL53 was found during testing of a group of clinical isolates for antibiotic and heavy metal ion resistance [ ]. The determinant of the strain's tellurite resistance was located on a large conjugative plasmid, and analyses showed the genes terB, terC, terD and terE were essential for conservation of this resistance. Members of this family contain a number of conserved aspartates which may be involved in metal ion binding.A TerC homologue is known from the chloroplast thylakoid membrane from Arabidopsiswhich is important for thylakoid membrane biogenesis in the developing chloroplast [ ]; it is required for insertion of proteins into the thylakoid membrane [].This entry represents a subset of TerC proteins which are mostly encoded on genes preceded by a structured RNA element known as the yybP-ykoY leader. The yybP-ykoY leader (also known as SraF) may function in the regulation of these genes as riboswitch [ ]. This entry also includes the putative membrane-bound redox modulator Alx [].
Short Name	Integral_membrane_TerC_rswitch