Protein Domain : Coiled-coil domain-containing protein 22 IPR008530

Type  Family
Description  Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex [ ]. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer [].This entry also includes CCDC22 homologues from animals and plants.
Short Name  CCDC22

0 Child Features

1 Gene Families

7 Genes

0 Ontology Annotations

0 Parent Features

4 Publications

USDA
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