Protein Domain : Glycine cleavage system T protein IPR006223

Type  Family
Description  The glycine cleavage system (GCS) is a multienzyme system composed of proteins P, H, T, and L, that catalyses the reversible oxidation of glycine. The T protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3+ dihydrolipoylprotein The glycine cleavage system is found in bacteria and the mitochondria of eukaryotes. Mutations in the human T-protein gene are known to cause nonketotic hyperglycinemia [].
Short Name  GCS_T

1 Child Features

1 Gene Families

6 Genes

2 Ontology Annotations

1 Parent Features

4 Publications

USDA
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