v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | The glycine cleavage system (GCS) is a multienzyme system composed of proteins P, H, T, and L, that catalyses the reversible oxidation of glycine. The T protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3+ dihydrolipoylprotein The glycine cleavage system is found in bacteria and the mitochondria of eukaryotes. Mutations in the human T-protein gene are known to cause nonketotic hyperglycinemia []. |
| Short Name | GCS_T |