Protein Domain : DNA repair protein Rev1 IPR012112

Type  Family
Description  Rev1 is a deoxycytidyl transferase involved in translesion DNA synthesis (TLS) pathway to bypass DNA lesions during replication [ ]. During TLS, Y-family DNA polymerase (Poleta, Polkappa, Poliota and Rev1) incorporates a nucleotide opposite the DNA lesion, and then Polzeta (consitst of Rev3 and Rev7) carries out primer extension. Rev1 is a unique member of the Y polymerase family, since its catalytic activity is limited to DNA-dependent, deoxycytidyl transferase activity [, , ].
Short Name  REV1

0 Child Features

1 Gene Families

6 Genes

4 Ontology Annotations

0 Parent Features

4 Publications

USDA
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