LIS - Legume Information System
Information about legume traits for crop improvement
CicerMine
v5.1.0.3
Cicer data from the Legume Information System
v5.1.0.3
Cicer data from the Legume Information System
| Type | Family |
| Description | Mre11 and Rad50 are two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae. Mre11 by itself has 3' to 5' exonuclease activity that is increased when Mre11 is in a complex with Rad50 [ ]. These eukaryotic proteins contain one metallo-phosphoesterase domain followed by an Mre11 DNA-binding domain. S. cerevisiae Mre11 is required for DNA repair and meiosis-specific double-strand break (DSB) formation [] and has both 3' to 5' exonuclease activity (whichincreases when in complex with Rad50) and endonuclease activity. The N-terminal phosphoesterase domain is required for DSB repair, and the carboxyl-terminal dsDNA-binding domain is essential during meiosis forchromatin modification and DSB formation [ ]. Schizosaccharomyces pombe rad32 is required for repair of double strand breaks and recombination []. |
| Short Name | Mre11 |
