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Search results 2501 to 2600 out of 44733 for *

Category restricted to GOTerm (x)

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Categories

Category: GOTerm
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Type Details Score
GO Term
GO:0000240 | diplotene
Description: The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.
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GO Term
GO:0000241 | diakinesis
Description: The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred.
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GO Term
GO:0000243 | commitment complex
Description: A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript.
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GO Term
GO:0000246 | delta24(24-1) sterol reductase activity
Description: Catalysis of the reaction: ergosterol + NADP(+) = ergosta-5,7,22,24(24(1))-tetraen-3beta-ol + H(+) + NADPH.
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GO Term
GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds
Description: Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more carbon-carbon double bonds in the molecule are rearranged, and no oxidized product appears.
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GO Term
GO:0000247 | C-8 sterol isomerase activity
Description: Catalysis of the reaction which results in unsaturation at C-7 in the B ring of sterols.
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GO Term
GO:0016860 | intramolecular oxidoreductase activity
Description: Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, and no oxidized product appears.
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GO Term
GO:0070704 | sterol desaturase activity
Description: Catalysis of the introduction of a double bond into a sterol molecule.
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GO Term
GO:0000248 | C-5 sterol desaturase activity
Description: Catalysis of the reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+.
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GO Term
GO:0000249 | C-22 sterol desaturase activity
Description: Catalysis of the formation of the C-22(23) double bond in the sterol side chain. An example reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+.
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GO Term
GO:0031559 | oxidosqualene cyclase activity
Description: Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene.
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GO Term
GO:0000250 | lanosterol synthase activity
Description: Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus.
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GO Term
GO:0000252 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
Description: Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H.
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GO Term
GO:0000254 | C-4 methylsterol oxidase activity
Description: Catalysis of the reaction: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)H + H(+) + O2 = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)+ + H2O.
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GO Term
GO:0017144 | drug metabolic process
Description: The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
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GO Term
GO:0043605 | cellular amide catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
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GO Term
GO:0042737 | drug catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of a drug, a substance used in the diagnosis, treatment or prevention of a disease.
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GO Term
GO:0016815 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles
Description: Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN.
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GO Term
GO:0000257 | nitrilase activity
Description: Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides.
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GO Term
GO:0042645 | mitochondrial nucleoid
Description: The region of a mitochondrion to which the DNA is confined.
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GO Term
GO:0000268 | peroxisome targeting sequence binding
Description: Interacting selectively and non-covalently with a peroxisomal targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome.
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GO Term
GO:0000269 | toxin export channel activity
Description: Enables the energy independent passage of toxins, sized less than 1000 Da, across a membrane towards the outside of the cell. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
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GO Term
GO:0000274 | mitochondrial proton-transporting ATP synthase, stator stalk
Description: One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core.
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GO Term
GO:0045265 | proton-transporting ATP synthase, stator stalk
Description: One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; is thought to prevent futile rotation of the catalytic core.
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GO Term
GO:0000282 | cellular bud site selection
Description: The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae.
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GO Term
GO:0110156 | methylguanosine-cap decapping
Description: Cleavage of the 5'-methylguanosine-cap of an mRNA. The methylguanosine-cap is present at the 5'-end of eukaryotic mRNAs. Decapping inactivates translation initiation and promotes 5'-to-3' decay of mRNA.
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GO Term
GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic
Description: The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap or the 3'-poly(A) tail.
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GO Term
GO:0000292 | RNA fragment catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing.
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GO Term
GO:0016723 | oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor
Description: Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and NAD+ or NADP+ acts as an electron acceptor.
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GO Term
GO:0000293 | ferric-chelate reductase activity
Description: Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H(+).
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GO Term
GO:0000294 | nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay
Description: A minor degradation pathway nuclear-transcribed mRNAs that begins with an endonucleolytic cleavage to generate unprotected ends.
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GO Term
GO:0000295 | adenine nucleotide transmembrane transporter activity
Description: Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other.
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GO Term
GO:0015215 | nucleotide transmembrane transporter activity
Description: Enables the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other.
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GO Term
GO:0015605 | organophosphate ester transmembrane transporter activity
Description: Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds.
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GO Term
GO:0000296 | spermine transport
Description: The directed movement of spermine, N,N-bis(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to spermidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
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GO Term
GO:0015893 | drug transport
Description: The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
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GO Term
GO:0042493 | response to drug
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
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GO Term
GO:0000297 | spermine transmembrane transporter activity
Description: Enables the transfer of spermine from one side of a membrane to the other. Spermine is a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.
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GO Term
GO:0000301 | retrograde transport, vesicle recycling within Golgi
Description: The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi.
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GO Term
GO:0000305 | response to oxygen radical
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.
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GO Term
GO:0000303 | response to superoxide
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
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GO Term
GO:0010035 | response to inorganic substance
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.
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GO Term
GO:0000304 | response to singlet oxygen
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.
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GO Term
GO:0031312 | extrinsic component of organelle membrane
Description: The component of an organelle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
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GO Term
GO:0000306 | extrinsic component of vacuolar membrane
Description: The component of a vacuolar membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
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GO Term
GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex
Description: Cyclin-dependent protein kinase (CDK) complex found in the cytoplasm.
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GO Term
GO:0106130 | purine phosphoribosyltransferase activity
Description: Catalysis of the reaction: RMP + diphosphate = R + 5-phospho-alpha-D-ribose 1-diphosphate.
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GO Term
GO:0009547 | plastid ribosome
Description: A ribosome contained within a plastid.
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GO Term
GO:0000311 | plastid large ribosomal subunit
Description: The larger of the two subunits of a plastid ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
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GO Term
GO:0000315 | organellar large ribosomal subunit
Description: The larger of the two subunits of an organellar ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
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GO Term
GO:0009532 | plastid stroma
Description: The proteinaceous ground substance of plastids.
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GO Term
GO:0000312 | plastid small ribosomal subunit
Description: The smaller of the two subunits of a plastid ribosome.
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GO Term
GO:0000314 | organellar small ribosomal subunit
Description: The smaller of the two subunits of an organellar ribosome.
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GO Term
GO:0000316 | sulfite transport
Description: The directed movement of sulfite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
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GO Term
GO:0000319 | sulfite transmembrane transporter activity
Description: Enables the transfer of sulfite ions from one side of a membrane to the other.
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GO Term
GO:0000320 | re-entry into mitotic cell cycle
Description: The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state.
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GO Term
GO:0000321 | re-entry into mitotic cell cycle after pheromone arrest
Description: The resumption of the mitotic cell division cycle by pheromone-arrested cells that have not mated. An example of this process is found in Saccharomyces cerevisiae.
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GO Term
GO:2000241 | regulation of reproductive process
Description: Any process that modulates the frequency, rate or extent of reproductive process.
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GO Term
GO:2000243 | positive regulation of reproductive process
Description: Any process that activates or increases the frequency, rate or extent of reproductive process.
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GO Term
GO:0043902 | positive regulation of multi-organism process
Description: Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
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GO Term
GO:0043900 | regulation of multi-organism process
Description: Any process that modulates the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
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GO Term
GO:0031136 | positive regulation of conjugation
Description: Any process that increases the rate or frequency of conjugation.
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GO Term
GO:0023058 | adaptation of signaling pathway
Description: The regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.
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GO Term
GO:0031139 | positive regulation of conjugation with cellular fusion
Description: Any process that increases the rate or frequency of conjugation with cellular fusion.
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GO Term
GO:0031137 | regulation of conjugation with cellular fusion
Description: Any process that modulates the rate or frequency of conjugation with cellular fusion.
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GO Term
GO:0071444 | cellular response to pheromone
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.
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GO Term
GO:0000749 | response to pheromone triggering conjugation with cellular fusion
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that positively regulates the process of conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.
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GO Term
GO:0000326 | protein storage vacuole
Description: A storage vacuole that contains a lytic vacuole; identified in plants.
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GO Term
GO:0000327 | lytic vacuole within protein storage vacuole
Description: A membrane-bounded compartment containing crystals of phytic acid and proteins characteristic of a lytic vacuole, found within a storage vacuole.
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GO Term
GO:0005775 | vacuolar lumen
Description: The volume enclosed within the vacuolar membrane.
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GO Term
GO:0000328 | fungal-type vacuole lumen
Description: The volume enclosed within the vacuolar membrane of a vacuole, the shape of which correlates with cell cycle phase. An example of this structure is found in Saccharomyces cerevisiae.
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GO Term
GO:0000330 | plant-type vacuole lumen
Description: The volume enclosed within the vacuolar membrane of a vacuole that retains the same shape regardless of cell cycle phase. An example of this is found in Arabidopsis thaliana.
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GO Term
GO:0000331 | contractile vacuole
Description: A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. One of its functions is osmoregulatory.
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GO Term
GO:0062159 | contractile vacuole complex
Description: A non-membrane-bounded organelle of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally. One of its functions is osmoregulatory.
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GO Term
GO:0000497 | DNA template activity
Description: Interacting selectively and non-covalently with nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target DNA molecule.
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GO Term
GO:0000332 | template for synthesis of G-rich strand of telomere DNA activity
Description: Provision of the template used by reverse transcriptase to synthesize the G-rich strand of telomeric DNA.
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GO Term
GO:0000333 | telomerase catalytic core complex
Description: The minimal catalytic core of telomerase is a ribonucleoprotein complex composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition.
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GO Term
GO:0000337 | regulation of transposition, DNA-mediated
Description: Any process that modulates the frequency, rate or extent of DNA transposition, the process of transposing (moving to a different location) a segment of a chromosome or a piece of a DNA molecule.
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GO Term
GO:0000335 | negative regulation of transposition, DNA-mediated
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA transposition.
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GO Term
GO:0010529 | negative regulation of transposition
Description: Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
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GO Term
GO:0010528 | regulation of transposition
Description: Any process that modulates the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
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GO Term
GO:0045911 | positive regulation of DNA recombination
Description: Any process that activates or increases the frequency, rate or extent of DNA recombination.
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GO Term
GO:0000336 | positive regulation of transposition, DNA-mediated
Description: Any process that activates or increases the frequency, rate or extent of DNA transposition.
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GO Term
GO:0010530 | positive regulation of transposition
Description: Any process that increases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
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GO Term
GO:0051054 | positive regulation of DNA metabolic process
Description: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.
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GO Term
GO:0000341 | RNA trimethylguanosine cap binding
Description: Interacting selectively and non-covalently with the trimethylguanosine (m(3)(2,2,7)-GTP) group located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans.
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GO Term
GO:0000342 | RNA cap 4 binding
Description: Interacting selectively and non-covalently with a hypermethylated cap structure consisting of 7-methylguanosine (m(7)G) followed by four methylated nucleotides (cap 4): 7-methylguanosine-ppp-N6, N6, 2'-O-trimethyladenosine-p-2'-O-methyladenosine-p-2'-O-methylcytosine-p-N3, 2'-O-dimethyluridine Such caps are known to be found at the 5' ends of SL RNAs of trypanosomatid protozoa.
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GO Term
GO:0000343 | plastid-encoded plastid RNA polymerase complex A
Description: A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-A is generated from the PEP-B form during chloroplast maturation to generate a complex composed of at least thirteen polypeptides that is not sensitive to the antibiotic rifampicin, like its precursor form the PEP-B complex.
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GO Term
GO:0000344 | plastid-encoded plastid RNA polymerase complex B
Description: A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-B is distinguished from PEP-A by its sensitivity to the antibiotic rifampicin. PEP-B is found in both etioplasts and chloroplasts, but is the predominate form in etioplasts. It forms the core of the PEP-A form; the conversion from PEP-B to PEP-A occurs during chloroplast maturation.
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GO Term
GO:0000345 | cytosolic DNA-directed RNA polymerase complex
Description: The eubacterial DNA-directed RNA polymerase is a multisubunit complex with a core composed of the essential subunits beta-prime, beta, and two copies of alpha and a fifth nonessential subunit called omega. An additional subunit, a sigma factor, is required for promoter recognition and specificity.
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GO Term
GO:0000348 | mRNA branch site recognition
Description: Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome.
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GO Term
GO:0000349 | generation of catalytic spliceosome for first transesterification step
Description: Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome.
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GO Term
GO:0000393 | spliceosomal conformational changes to generate catalytic conformation
Description: Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation.
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GO Term
GO:0045291 | mRNA trans splicing, SL addition
Description: The joining together of two independently transcribed RNAs, where the one that provides the 5' portion of the final mRNA is from a splice leader RNA (SL-RNA). The SL-RNA, or mini-exon donor sequence, is added to the 5'-end of the acceptor RNA molecule which provides the mRNA body.
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GO Term
GO:0000352 | trans assembly of SL-containing precatalytic spliceosome
Description: Assembly of a spliceosomal complex containing the SL RNA and the pre-mRNA to be joined, as well as all the spliceosomal snRNPs involved in trans leader splicing. Formation of the trans leader spliceosome brings together the quadruple SL/U4/U5/U6 snRNP and the complex of the U2 snRNP with the splice site of the pre-mRNA.
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GO Term
GO:0000365 | mRNA trans splicing, via spliceosome
Description: The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
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GO Term
GO:0000353 | formation of quadruple SL/U4/U5/U6 snRNP
Description: Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA.
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GO Term
GO:0000354 | cis assembly of pre-catalytic spliceosome
Description: Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.
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GO Term
GO:0000366 | intergenic mRNA trans splicing
Description: The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing.
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GO Term
GO:0000376 | RNA splicing, via transesterification reactions with guanosine as nucleophile
Description: Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile.
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