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Search results 44601 to 44700 out of 44733 for *

Category restricted to GOTerm (x)

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Categories

Category: GOTerm
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Type Details Score
GO Term
GO:0032328 | alanine transport
Description: The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
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GO Term
GO:0016917 | GABA receptor activity
Description: Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms.
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GO Term
GO:0007270 | neuron-neuron synaptic transmission
Description: The process of synaptic transmission from a neuron to another neuron across a synapse.
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GO Term
GO:0043405 | regulation of MAP kinase activity
Description: Any process that modulates the frequency, rate or extent of MAP kinase activity.
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GO Term
GO:0043542 | endothelial cell migration
Description: The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
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GO Term
GO:0097530 | granulocyte migration
Description: The movement of a granulocyte within or between different tissues and organs of the body.
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GO Term
GO:0097529 | myeloid leukocyte migration
Description: The movement of a myeloid leukocyte within or between different tissues and organs of the body.
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GO Term
GO:0048246 | macrophage chemotaxis
Description: The movement of a macrophage in response to an external stimulus.
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GO Term
GO:0050918 | positive chemotaxis
Description: The directed movement of a motile cell or organism towards a higher concentration of a chemical.
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GO Term
GO:0045037 | protein import into chloroplast stroma
Description: The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import.
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GO Term
GO:0008593 | regulation of Notch signaling pathway
Description: Any process that modulates the frequency, rate or extent of the Notch signaling pathway.
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GO Term
GO:0005684 | U2-type spliceosomal complex
Description: Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.
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GO Term
GO:0008625 | extrinsic apoptotic signaling pathway via death domain receptors
Description: A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered.
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GO Term
GO:0043281 | regulation of cysteine-type endopeptidase activity involved in apoptotic process
Description: Any process that modulates the activity of a cysteine-type endopeptidase involved in apoptosis.
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GO Term
GO:0070936 | protein K48-linked ubiquitination
Description: A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
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GO Term
GO:0061631 | ubiquitin conjugating enzyme activity
Description: Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.
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GO Term
GO:0061650 | ubiquitin-like protein conjugating enzyme activity
Description: Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction X-SCP + Y -> Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue.
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GO Term
GO:0050431 | transforming growth factor beta binding
Description: Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.
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GO Term
GO:0071559 | response to transforming growth factor beta
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
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GO Term
GO:0071560 | cellular response to transforming growth factor beta stimulus
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
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GO Term
GO:0010811 | positive regulation of cell-substrate adhesion
Description: Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
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GO Term
GO:0071004 | U2-type prespliceosome
Description: A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.
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GO Term
GO:0070971 | endoplasmic reticulum exit site
Description: An endoplasmic reticulum part at which COPII-coated vesicles are produced.
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GO Term
GO:0035304 | regulation of protein dephosphorylation
Description: Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein.
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GO Term
GO:0016796 | exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
Description: Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.
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GO Term
GO:0140297 | DNA-binding transcription factor binding
Description: Interacting selectively and non-covalently with a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription.
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GO Term
GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity
Description: Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.
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GO Term
GO:0035088 | establishment or maintenance of apical/basal cell polarity
Description: Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components.
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GO Term
GO:0061245 | establishment or maintenance of bipolar cell polarity
Description: Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns.
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GO Term
GO:0070555 | response to interleukin-1
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.
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GO Term
GO:0031901 | early endosome membrane
Description: The lipid bilayer surrounding an early endosome.
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GO Term
GO:0032185 | septin cytoskeleton organization
Description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising septin complexes and their associated proteins.
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GO Term
GO:0032392 | DNA geometric change
Description: The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases.
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GO Term
GO:0006521 | regulation of cellular amino acid metabolic process
Description: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids.
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GO Term
GO:0045851 | pH reduction
Description: Any process that reduces the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.
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GO Term
GO:0007035 | vacuolar acidification
Description: Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion.
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GO Term
GO:0008227 | G protein-coupled amine receptor activity
Description: Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
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GO Term
GO:0019233 | sensory perception of pain
Description: The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
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GO Term
GO:0031501 | mannosyltransferase complex
Description: A complex that posseses mannosyltransferase activity.
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GO Term
GO:0043204 | perikaryon
Description: The portion of the cell soma (neuronal cell body) that excludes the nucleus.
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GO Term
GO:0051427 | hormone receptor binding
Description: Interacting selectively and non-covalently with a receptor for hormones.
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GO Term
GO:0045165 | cell fate commitment
Description: The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
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GO Term
GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Description: A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.
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GO Term
GO:2001242 | regulation of intrinsic apoptotic signaling pathway
Description: Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway.
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GO Term
GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator
Description: A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.
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GO Term
GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway
Description: Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway.
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GO Term
GO:0007274 | neuromuscular synaptic transmission
Description: The process of synaptic transmission from a neuron to a muscle, across a synapse.
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GO Term
GO:0000963 | mitochondrial RNA processing
Description: The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion.
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GO Term
GO:0043186 | P granule
Description: A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
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GO Term
GO:0046427 | positive regulation of receptor signaling pathway via JAK-STAT
Description: Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.
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GO Term
GO:0043491 | protein kinase B signaling
Description: A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.
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GO Term
GO:0051896 | regulation of protein kinase B signaling
Description: Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
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GO Term
GO:0046033 | AMP metabolic process
Description: The chemical reactions and pathways involving AMP, adenosine monophosphate.
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GO Term
GO:0018107 | peptidyl-threonine phosphorylation
Description: The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
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GO Term
GO:0007271 | synaptic transmission, cholinergic
Description: The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
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GO Term
GO:0034587 | piRNA metabolic process
Description: The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
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GO Term
GO:0035567 | non-canonical Wnt signaling pathway
Description: The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin.
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GO Term
GO:0016064 | immunoglobulin mediated immune response
Description: An immune response mediated by immunoglobulins, whether cell-bound or in solution.
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GO Term
GO:0060170 | ciliary membrane
Description: The portion of the plasma membrane surrounding a cilium.
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GO Term
GO:0009705 | plant-type vacuole membrane
Description: The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana.
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GO Term
GO:0030331 | estrogen receptor binding
Description: Interacting selectively and non-covalently with an estrogen receptor.
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GO Term
GO:0030518 | intracellular steroid hormone receptor signaling pathway
Description: A series of molecular signals generated as a consequence of a intracellular steroid hormone receptor binding to one of its physiological ligands.
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GO Term
GO:0018345 | protein palmitoylation
Description: The covalent attachment of a palmitoyl group to a protein.
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GO Term
GO:2001259 | positive regulation of cation channel activity
Description: Any process that activates or increases the frequency, rate or extent of cation channel activity.
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GO Term
GO:1902652 | secondary alcohol metabolic process
Description: The chemical reactions and pathways involving secondary alcohol.
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GO Term
GO:0006706 | steroid catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
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GO Term
GO:2001238 | positive regulation of extrinsic apoptotic signaling pathway
Description: Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway.
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GO Term
GO:0050679 | positive regulation of epithelial cell proliferation
Description: Any process that activates or increases the rate or extent of epithelial cell proliferation.
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GO Term
GO:0050673 | epithelial cell proliferation
Description: The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.
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GO Term
GO:0008066 | glutamate receptor activity
Description: Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
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GO Term
GO:0043473 | pigmentation
Description: The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.
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GO Term
GO:0032438 | melanosome organization
Description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.
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GO Term
GO:0007379 | segment specification
Description: The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes.
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GO Term
GO:0007502 | digestive tract mesoderm development
Description: The process whose specific outcome is the progression of the digestive tract mesoderm over time, from its formation to the mature structure. The digestive tract mesoderm is portion of the middle layer of the three primary germ layers of the embryo which will go on to form part of the digestive tract of the organism.
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GO Term
GO:0015203 | polyamine transmembrane transporter activity
Description: Enables the transfer of polyamines, organic compounds containing two or more amino groups, from one side of a membrane to the other.
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GO Term
GO:0022624 | proteasome accessory complex
Description: A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex.
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GO Term
GO:0034704 | calcium channel complex
Description: An ion channel complex through which calcium ions pass.
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GO Term
GO:0036293 | response to decreased oxygen levels
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.
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GO Term
GO:0001666 | response to hypoxia
Description: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
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GO Term
GO:0071456 | cellular response to hypoxia
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
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GO Term
GO:0017015 | regulation of transforming growth factor beta receptor signaling pathway
Description: Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.
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GO Term
GO:1903844 | regulation of cellular response to transforming growth factor beta stimulus
Description: Any process that modulates the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.
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GO Term
GO:0051294 | establishment of spindle orientation
Description: Any process that set the alignment of spindle relative to other cellular structures.
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GO Term
GO:0008298 | intracellular mRNA localization
Description: Any process in which mRNA is transported to, or maintained in, a specific location within the cell.
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GO Term
GO:0045103 | intermediate filament-based process
Description: Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins.
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GO Term
GO:0099061 | integral component of postsynaptic density membrane
Description: The component of the postsynaptic density membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
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GO Term
GO:0030195 | negative regulation of blood coagulation
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.
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GO Term
GO:0034212 | peptide N-acetyltransferase activity
Description: Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide.
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GO Term
GO:0043966 | histone H3 acetylation
Description: The modification of histone H3 by the addition of an acetyl group.
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GO Term
GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Description: A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
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GO Term
GO:0006336 | DNA replication-independent nucleosome assembly
Description: The formation of nucleosomes outside the context of DNA replication.
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GO Term
GO:0034724 | DNA replication-independent nucleosome organization
Description: The formation or destruction of chromatin structures, occurring outside the context of DNA replication.
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GO Term
GO:0098781 | ncRNA transcription
Description: The transcription of non (protein) coding RNA from a DNA template.
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GO Term
GO:0001163 | RNA polymerase I regulatory region sequence-specific DNA binding
Description: Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase I.
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GO Term
GO:0046461 | neutral lipid catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only soluble in solvents of very low polarity.
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GO Term
GO:0046464 | acylglycerol catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
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GO Term
GO:0046128 | purine ribonucleoside metabolic process
Description: The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.
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GO Term
GO:0101031 | chaperone complex
Description: A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins.
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GO Term
GO:0042795 | snRNA transcription by RNA polymerase II
Description: The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.
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GO Term
GO:0034394 | protein localization to cell surface
Description: A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane.
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