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Search results 42201 to 42300 out of 44733 for *

Category restricted to GOTerm (x)

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Categories

Category: GOTerm
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Type Details Score
GO Term
GO:0071013 | catalytic step 2 spliceosome
Description: A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
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GO Term
GO:0040021 | hermaphrodite germ-line sex determination
Description: The determination of sex and sexual phenotype in the germ line of a hermaphrodite.
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GO Term
GO:0042001 | hermaphrodite somatic sex determination
Description: The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans.
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GO Term
GO:0006307 | DNA dealkylation involved in DNA repair
Description: The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA alkyltransferase (AGT).
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GO Term
GO:0035552 | oxidative single-stranded DNA demethylation
Description: Removal of the methyl group from one or more nucleotides within a single-stranded DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.
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GO Term
GO:0070988 | demethylation
Description: The process of removing one or more methyl groups from a molecule.
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GO Term
GO:0035515 | oxidative RNA demethylase activity
Description: Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.
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GO Term
GO:0035553 | oxidative single-stranded RNA demethylation
Description: Removal of the methyl group from one or more nucleotides within a single-stranded RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.
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GO Term
GO:0035516 | oxidative DNA demethylase activity
Description: Catalysis of the removal of the methyl group from one or more nucleotides within a DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.
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GO Term
GO:0040014 | regulation of multicellular organism growth
Description: Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
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GO Term
GO:0042245 | RNA repair
Description: Any process that results in the repair of damaged RNA.
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GO Term
GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death
Description: Any regulation of mitochondrial membrane permeability that is involved in programmed necrotic cell death.
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GO Term
GO:0089714 | UDP-N-acetyl-D-mannosamine dehydrogenase activity
Description: Catalysis of the reaction: UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+.
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GO Term
GO:0019180 | dTDP-4-amino-4,6-dideoxygalactose transaminase activity
Description: Catalysis of the reaction: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-D-galactose = L-glutamate + dTDP-4-dehydro-6-deoxy-D-galactose.
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GO Term
GO:0016002 | sulfite reductase activity
Description: Catalysis of the reaction: hydrogen sulfide + acceptor + 3 H2O = sulfite + reduced acceptor.
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GO Term
GO:0070814 | hydrogen sulfide biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.
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GO Term
GO:0032506 | cytokinetic process
Description: A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells).
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GO Term
GO:0030428 | cell septum
Description: A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
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GO Term
GO:0031638 | zymogen activation
Description: The proteolytic processing of an inactive enzyme to an active form.
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GO Term
GO:0035226 | glutamate-cysteine ligase catalytic subunit binding
Description: Interacting selectively and non-covalently with the catalytic subunit of glutamate-cysteine ligase.
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GO Term
GO:0008046 | axon guidance receptor activity
Description: Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance.
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GO Term
GO:0016199 | axon midline choice point recognition
Description: The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline.
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GO Term
GO:0035385 | Roundabout signaling pathway
Description: A series of molecular signals initiated by the binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
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GO Term
GO:0010997 | anaphase-promoting complex binding
Description: Interacting selectively and non-covalently with an anaphase-promoting complex. A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis.
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GO Term
GO:0097027 | ubiquitin-protein transferase activator activity
Description: Increases the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein.
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GO Term
GO:1904668 | positive regulation of ubiquitin protein ligase activity
Description: Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity.
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GO Term
GO:0061780 | mitotic cohesin loading
Description: The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA as part of the mitotic cell cycle.
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GO Term
GO:0032021 | NELF complex
Description: A complex of five proteins, designated NELF-A, -B, -C, -D, and -E in human, that can physically associate with RNP polymerase II to induce transcriptional pausing.
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GO Term
GO:0045595 | regulation of cell differentiation
Description: Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.
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GO Term
GO:0061564 | axon development
Description: The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation).
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GO Term
GO:0005883 | neurofilament
Description: A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter.
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GO Term
GO:0036158 | outer dynein arm assembly
Description: The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.
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GO Term
GO:0015067 | amidinotransferase activity
Description: Catalysis of the reversible transfer of an amidino group to an acceptor.
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GO Term
GO:0045109 | intermediate filament organization
Description: Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
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GO Term
GO:0051298 | centrosome duplication
Description: The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
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GO Term
GO:0005814 | centriole
Description: A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
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GO Term
GO:1901222 | regulation of NIK/NF-kappaB signaling
Description: Any process that modulates the frequency, rate or extent of NIK/NF-kappaB signaling.
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GO Term
GO:0016079 | synaptic vesicle exocytosis
Description: Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft.
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GO Term
GO:1990504 | dense core granule exocytosis
Description: The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels.
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GO Term
GO:0045666 | positive regulation of neuron differentiation
Description: Any process that activates or increases the frequency, rate or extent of neuron differentiation.
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GO Term
GO:0045930 | negative regulation of mitotic cell cycle
Description: Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle.
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GO Term
GO:0010921 | regulation of phosphatase activity
Description: Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
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GO Term
GO:0009631 | cold acclimation
Description: Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures.
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GO Term
GO:0010150 | leaf senescence
Description: The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.
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GO Term
GO:0042023 | DNA endoreduplication
Description: Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.
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GO Term
GO:0009330 | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex
Description: Complex that possesses DNA topoisomerase II (double strand cut, ATP-hydrolyzing) activity.
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GO Term
GO:0048731 | system development
Description: The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
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GO Term
GO:0032797 | SMN complex
Description: A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus.
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GO Term
GO:0043029 | T cell homeostasis
Description: The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
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GO Term
GO:0050863 | regulation of T cell activation
Description: Any process that modulates the frequency, rate or extent of T cell activation.
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GO Term
GO:0046621 | negative regulation of organ growth
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.
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GO Term
GO:0036159 | inner dynein arm assembly
Description: The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.
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GO Term
GO:0005930 | axoneme
Description: The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
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GO Term
GO:0048476 | Holliday junction resolvase complex
Description: An endodeoxyribonuclease complex that resolves the 4-way DNA intermediates of a Holliday junction into two separate duplex DNA molecules. Can be branch-migration associated.
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GO Term
GO:0080008 | Cul4-RING E3 ubiquitin ligase complex
Description: A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
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GO Term
GO:0051513 | regulation of monopolar cell growth
Description: Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.
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GO Term
GO:0048168 | regulation of neuronal synaptic plasticity
Description: A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
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GO Term
GO:2001222 | regulation of neuron migration
Description: Any process that modulates the frequency, rate or extent of neuron migration.
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GO Term
GO:0005892 | acetylcholine-gated channel complex
Description: A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.
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GO Term
GO:0035278 | miRNA mediated inhibition of translation
Description: The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs
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GO Term
GO:0030576 | Cajal body organization
Description: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors.
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GO Term
GO:0072572 | poly-ADP-D-ribose binding
Description: Interacting selectively and non-covalently with polymeric ADP-D-ribose, a polymer that is composed of poly-ADP-D-ribose units linked through 1,2-glycosidic bonds at the ribose ring.
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GO Term
GO:0007162 | negative regulation of cell adhesion
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
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GO Term
GO:0000711 | meiotic DNA repair synthesis
Description: During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template.
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GO Term
GO:0071300 | cellular response to retinoic acid
Description: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
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GO Term
GO:1903575 | cornified envelope assembly
Description: The aggregation, arrangement and bonding together of a set of components to form a cornified envelope.
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GO Term
GO:0045577 | regulation of B cell differentiation
Description: Any process that modulates the frequency, rate or extent of B cell differentiation.
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GO Term
GO:0050861 | positive regulation of B cell receptor signaling pathway
Description: Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
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GO Term
GO:0008970 | phospholipase A1 activity
Description: Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate.
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GO Term
GO:0090162 | establishment of epithelial cell polarity
Description: The specification and formation of anisotropic intracellular organization of an epithelial cell.
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GO Term
GO:0097539 | ciliary transition fiber
Description: A nine-bladed, propeller-like protein complex that links the distal end of the basal body and the cilium to the plasma membrane. Functions in protein sorting and gating (i.e. active and passive transport of proteins in and out of the cilium).
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GO Term
GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process
Description: Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
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GO Term
GO:0000183 | chromatin silencing at rDNA
Description: Repression of transcription of ribosomal DNA by altering the structure of chromatin.
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GO Term
GO:0000792 | heterochromatin
Description: A compact and highly condensed form of chromatin.
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GO Term
GO:0007127 | meiosis I
Description: The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei.
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GO Term
GO:0001188 | RNA polymerase I preinitiation complex assembly
Description: The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase I promoter.
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GO Term
GO:1904262 | negative regulation of TORC1 signaling
Description: Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling.
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GO Term
GO:0034784 | pivalyl-CoA mutase activity
Description: Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA.
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GO Term
GO:0047727 | isobutyryl-CoA mutase activity
Description: Catalysis of the reaction: isobutyryl-CoA = butanoyl-CoA.
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GO Term
GO:0019367 | fatty acid elongation, saturated fatty acid
Description: Elongation of a saturated fatty acid chain.
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GO Term
GO:0042761 | very long-chain fatty acid biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of a fatty acid which has a chain length greater than C22.
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GO Term
GO:0071518 | autoinducer-2 kinase activity
Description: Catalysis of the reaction: 4,5-dihydroxy-pentane-2,3-dione + ATP = 5-phospho-4-hydroxy-pentane-2,3-dione (P-DPD) + ADP.
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GO Term
GO:0019706 | protein-cysteine S-palmitoyltransferase activity
Description: Catalysis of the transfer of a palmitoyl group to a sulfur atom on the cysteine of a protein molecule.
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GO Term
GO:0039686 | bidirectional double-stranded viral DNA replication
Description: A viral DNA replication process where replication occurs in both directions from the starting point. This creates two replication forks, moving in opposite directions.
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GO Term
GO:0004787 | thiamine-pyrophosphatase activity
Description: Catalysis of the reaction: TDP + H2O = TMP + phosphate.
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GO Term
GO:0035194 | posttranscriptional gene silencing by RNA
Description: Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger RNA (often mRNA) degradation or negatively regulate mRNA translation.
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GO Term
GO:1900723 | negative regulation of protein adenylylation
Description: Any process that stops, prevents or reduces the frequency, rate or extent of protein adenylylation.
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GO Term
GO:0033736 | L-lysine 6-oxidase activity
Description: Catalysis of the reaction: L-lysine + H(2)O + O(2) = allysine + H(2)O(2) + NH(4)(+).
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GO Term
GO:1900191 | negative regulation of single-species biofilm formation
Description: Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation.
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GO Term
GO:0004530 | deoxyribonuclease I activity
Description: Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products.
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GO Term
GO:0004549 | tRNA-specific ribonuclease activity
Description: Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules.
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GO Term
GO:0051097 | negative regulation of helicase activity
Description: Any process that stops or reduces the activity of a helicase.
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GO Term
GO:0035262 | gonad morphogenesis
Description: The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.
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GO Term
GO:0000324 | fungal-type vacuole
Description: A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
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GO Term
GO:0050769 | positive regulation of neurogenesis
Description: Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
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GO Term
GO:0051918 | negative regulation of fibrinolysis
Description: Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
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GO Term
GO:0042730 | fibrinolysis
Description: A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin.
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GO Term
GO:0016657 | oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor
Description: Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a nitrogenous group.
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GO Term
GO:0001054 | RNA polymerase I activity
Description: Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase I specific promoter to direct initiation and catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
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GO Term
GO:0001056 | RNA polymerase III activity
Description: Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase III specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
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