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Search results 2101 to 2200 out of 44733 for *

Category restricted to GOTerm (x)

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Categories

Category: GOTerm
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Type Details Score
GO Term
GO:0050567 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
Description: Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP.
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GO Term
GO:0016925 | protein sumoylation
Description: The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.
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GO Term
GO:2000123 | positive regulation of stomatal complex development
Description: Any process that activates or increases the frequency, rate or extent of stomatal complex development.
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GO Term
GO:0035065 | regulation of histone acetylation
Description: Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein.
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GO Term
GO:0019903 | protein phosphatase binding
Description: Interacting selectively and non-covalently with any protein phosphatase.
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GO Term
GO:0006654 | phosphatidic acid biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
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GO Term
GO:0048017 | inositol lipid-mediated signaling
Description: A series of molecular signals in which a cell uses an inositol-containing lipid to convert a signal into a response. Inositol lipids include the phosphoinositides (phosphatidylinositol and its phosphorylated derivatives), ceramides containing inositol, and inositol glycolipids.
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GO Term
GO:1901671 | positive regulation of superoxide dismutase activity
Description: Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity.
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GO Term
GO:0001505 | regulation of neurotransmitter levels
Description: Any process that modulates levels of neurotransmitter.
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GO Term
GO:0004969 | histamine receptor activity
Description: Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
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GO Term
GO:0005747 | mitochondrial respiratory chain complex I
Description: A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
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GO Term
GO:0016603 | glutaminyl-peptide cyclotransferase activity
Description: Catalysis of the reaction: L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH3.
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GO Term
GO:0017186 | peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase
Description: The chemical reactions and pathways resulting in the formation of peptidyl-pyroglutamic acid, catalyzed by glutaminyl-peptide cyclotransferase.
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GO Term
GO:0030124 | AP-4 adaptor complex
Description: An AP-type membrane coat adaptor complex that consists of beta4, epsilon, mu4 and sigma4 subunits and is found associated with membranes in the trans-Golgi network; it is not clear whether AP-4 forms clathrin coats in vivo.
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GO Term
GO:0006884 | cell volume homeostasis
Description: Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell.
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GO Term
GO:0034709 | methylosome
Description: A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains.
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GO Term
GO:0034715 | pICln-Sm protein complex
Description: A protein complex that contains pICln (CLNS1A) and several Sm proteins, including SmD1, SmD2, SmE, SmF, and SmG.
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GO Term
GO:0098656 | anion transmembrane transport
Description: The process in which an anion is transported across a membrane.
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GO Term
GO:1901135 | carbohydrate derivative metabolic process
Description: The chemical reactions and pathways involving carbohydrate derivative.
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GO Term
GO:0097367 | carbohydrate derivative binding
Description: Interacting selectively and non-covalently with a carbohydrate derivative.
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GO Term
GO:0009226 | nucleotide-sugar biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.
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GO Term
GO:0000123 | histone acetyltransferase complex
Description: A protein complex that possesses histone acetyltransferase activity.
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GO Term
GO:0019348 | dolichol metabolic process
Description: The chemical reactions and pathways involving dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.
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GO Term
GO:0000245 | spliceosomal complex assembly
Description: The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions.
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GO Term
GO:0070481 | nuclear-transcribed mRNA catabolic process, non-stop decay
Description: The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon.
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GO Term
GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay
Description: The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.
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GO Term
GO:0071025 | RNA surveillance
Description: The set of processes involved in identifying and degrading defective or aberrant RNAs.
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GO Term
GO:0018026 | peptidyl-lysine monomethylation
Description: The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine.
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GO Term
GO:0043190 | ATP-binding cassette (ABC) transporter complex
Description: A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
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GO Term
GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly
Description: The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane.
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GO Term
GO:0045048 | protein insertion into ER membrane
Description: The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane.
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GO Term
GO:0000150 | recombinase activity
Description: Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA.
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GO Term
GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway
Description: The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.
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GO Term
GO:0051723 | protein methylesterase activity
Description: Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol.
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GO Term
GO:0050992 | dimethylallyl diphosphate biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate.
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GO Term
GO:0051745 | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity
Description: Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H + H+ = isopentenyl diphosphate + NAD(P)+ + H2O. Note that (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate is an alternative name for 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
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GO Term
GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
Description: The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.
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GO Term
GO:0006285 | base-excision repair, AP site formation
Description: The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired.
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GO Term
GO:0005832 | chaperonin-containing T-complex
Description: A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.
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GO Term
GO:0071897 | DNA biosynthetic process
Description: The cellular DNA metabolic process resulting in the formation of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.
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GO Term
GO:0016166 | phytoene dehydrogenase activity
Description: Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene.
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GO Term
GO:0090114 | COPII-coated vesicle budding
Description: The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle.
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GO Term
GO:0035598 | N6-threonylcarbomyladenosine methylthiotransferase activity
Description: Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-threonylcarbomyladenosine (t6A) in tRNA, to form 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A).
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GO Term
GO:0035600 | tRNA methylthiolation
Description: The addition of a methylthioether group (-SCH3) to a nucleotide in a tRNA molecule.
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GO Term
GO:0030289 | protein phosphatase 4 complex
Description: A protein serine/threonine phosphatase complex formed by the catalytic subunit of protein phosphatase 4 plus one or more regulatory subunits.
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GO Term
GO:0017121 | plasma membrane phospholipid scrambling
Description: The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE).
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GO Term
GO:0017128 | phospholipid scramblase activity
Description: Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism.
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GO Term
GO:0004318 | enoyl-[acyl-carrier-protein] reductase (NADH) activity
Description: Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+.
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GO Term
GO:0030686 | 90S preribosome
Description: A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.
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GO Term
GO:0006623 | protein targeting to vacuole
Description: The process of directing proteins towards the vacuole, usually using signals contained within the protein.
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GO Term
GO:0030122 | AP-2 adaptor complex
Description: A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).
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GO Term
GO:0035615 | clathrin adaptor activity
Description: Bringing together a cargo protein with clathrin, responsible for the formation of endocytic vesicles.
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GO Term
GO:0072583 | clathrin-dependent endocytosis
Description: An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
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GO Term
GO:0043625 | delta DNA polymerase complex
Description: A multimeric DNA polymerase enzyme complex which differs in composition amongst species; in humans it is a heterotetramer of four subunits of approximately 125, 50, 68 and 12kDa, while in S. cerevisiae, it has three different subunits which form a heterotrimer, and the active enzyme is a dimer of this heterotrimer. Functions in DNA replication, mismatch repair and excision repair.
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GO Term
GO:0032559 | adenyl ribonucleotide binding
Description: Interacting selectively and non-covalently with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
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GO Term
GO:0019948 | SUMO activating enzyme activity
Description: Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.
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GO Term
GO:0016435 | rRNA (guanine) methyltransferase activity
Description: Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine.
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GO Term
GO:0070476 | rRNA (guanine-N7)-methylation
Description: The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule.
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GO Term
GO:0001401 | SAM complex
Description: A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex.
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GO Term
GO:0034998 | oligosaccharyltransferase I complex
Description: An oligosaccharyltransferase (OST) complex that contains at least seven polypeptides and is the major OST complex in mammalian cells. Of the three forms of mammalian OST complex identified, the OSTI complex has the weakest affinity for ribosomes.
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GO Term
GO:1990426 | mitotic recombination-dependent replication fork processing
Description: Replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart.
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GO Term
GO:0009264 | deoxyribonucleotide catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
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GO Term
GO:0003688 | DNA replication origin binding
Description: Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.
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GO Term
GO:0017196 | N-terminal peptidyl-methionine acetylation
Description: The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine.
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GO Term
GO:0031417 | NatC complex
Description: A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Ile, Met-Leu, Met-Trp, or Met-Phe N-terminus. In Saccharomyces the complex includes Mak3p, Mak10p, and Mak31p.
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GO Term
GO:0008863 | formate dehydrogenase (NAD+) activity
Description: Catalysis of the reaction: formate + NAD(+) = CO(2) + NADH.
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GO Term
GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
Description: An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI anchors for cell surface proteins. The complex contains PIG-A, PIG-C, PIG-H, PIG-Q, PIG-P, and DPM2 in human, and Eri1p, Gpi1p, Gpi2p, Gpi15p, Gpi19p, and Spt14p in budding yeast.
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GO Term
GO:0010387 | COP9 signalosome assembly
Description: The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome.
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GO Term
GO:0030148 | sphingolipid biosynthetic process
Description: The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
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GO Term
GO:0042284 | sphingolipid delta-4 desaturase activity
Description: Catalysis of the introduction of a trans double bond between C4 and C5 of the long chain base region of a sphingolipid. Sphingolipids are composed of a long chain base (LCB) amide-linked to a very long chain fatty acid.
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GO Term
GO:0008134 | transcription factor binding
Description: Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
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GO Term
GO:0048487 | beta-tubulin binding
Description: Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin.
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GO Term
GO:0070536 | protein K63-linked deubiquitination
Description: A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.
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GO Term
GO:0051315 | attachment of mitotic spindle microtubules to kinetochore
Description: The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression.
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GO Term
GO:0035145 | exon-exon junction complex
Description: A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.
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GO Term
GO:0032469 | endoplasmic reticulum calcium ion homeostasis
Description: Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings.
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GO Term
GO:0033499 | galactose catabolic process via UDP-galactose
Description: The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose.
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GO Term
GO:0008622 | epsilon DNA polymerase complex
Description: A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair.
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GO Term
GO:0050518 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Description: Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + CTP = 4-CDP-2-C-methyl-D-erythritol + diphosphate.
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GO Term
GO:0070567 | cytidylyltransferase activity
Description: Catalysis of the transfer of a cytidylyl group to an acceptor.
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GO Term
GO:0000408 | EKC/KEOPS complex
Description: A protein complex involved in t6A tRNA modification; originally proposed to be involved in transcription as well as promoting telomere uncapping and telomere elongation. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon7p, Cgi121p, and Pcc1p.
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GO Term
GO:0002949 | tRNA threonylcarbamoyladenosine modification
Description: The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).
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GO Term
GO:0051321 | meiotic cell cycle
Description: Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
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GO Term
GO:0045275 | respiratory chain complex III
Description: A protein complex that transfers electrons from ubiquinol to cytochrome c and translocates two protons across a membrane. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome c1, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species.
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GO Term
GO:0008452 | RNA ligase activity
Description: Catalysis of the formation of a phosphodiester bond between a hydroxyl group at the end of one RNA chain and the 5'-phosphate group at the end of another.
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GO Term
GO:0009159 | deoxyribonucleoside monophosphate catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.
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GO Term
GO:0050144 | nucleoside deoxyribosyltransferase activity
Description: Catalysis of the reaction: 2-deoxy-D-ribosyl-base1 + base2 = 2-deoxy-D-ribosyl-base2 + base1.
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GO Term
GO:0070694 | deoxyribonucleoside 5'-monophosphate N-glycosidase activity
Description: Catalysis of the reaction: a deoxyribonucleoside 5'-monophosphate + H2O = deoxyribose 5-monophosphate + a purine or pyrimidine base.
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GO Term
GO:0008745 | N-acetylmuramoyl-L-alanine amidase activity
Description: Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides.
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GO Term
GO:0009253 | peptidoglycan catabolic process
Description: The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
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GO Term
GO:0006323 | DNA packaging
Description: Any process in which DNA and associated proteins are formed into a compact, orderly structure.
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GO Term
GO:0008608 | attachment of spindle microtubules to kinetochore
Description: The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex.
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GO Term
GO:0042729 | DASH complex
Description: A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability.
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GO Term
GO:0072686 | mitotic spindle
Description: A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
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GO Term
GO:0051056 | regulation of small GTPase mediated signal transduction
Description: Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.
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GO Term
GO:0004845 | uracil phosphoribosyltransferase activity
Description: Catalysis of the reaction: diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil.
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GO Term
GO:0006223 | uracil salvage
Description: Any process that generates uracil, 2,4-dioxopyrimidine, from derivatives of it without de novo synthesis.
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GO Term
GO:0016899 | oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
Description: Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an oxygen molecule.
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GO Term
GO:0016879 | ligase activity, forming carbon-nitrogen bonds
Description: Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
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GO Term
GO:0016530 | metallochaperone activity
Description: Directly binding to and delivering metal ions to a target protein.
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The Legume Information System (LIS) is a research project of the USDA-ARS:Corn Insects and Crop Genetics Research in Ames, IA.
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